Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.33 |
| ▸ | HTR6 | P50406 | 2/20 | 0.32 |
| ▸ | STAT3 | P40763 | 2/20 | 0.32 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | STAT5B | P51692 | 2/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14779678 | 0.94 | L3MBTL1 (0.33) | STAT3L3MBTL1STAT5B | |
| SCHEMBL1536129 | 0.90 | GRIN2B (0.39) | GPR119HTR6ADAM17MMP13BCHE | |
| SCHEMBL23404278 | 0.89 | L3MBTL1 (0.32) | STAT3L3MBTL1STAT5B | |
| SCHEMBL14779159 | 0.89 | L3MBTL1 (0.32) | STAT3L3MBTL1STAT5B | |
| SCHEMBL4352397 | 0.87 | ADAM17 (0.32) | GPR119HTR6ADAM17BCHE | |
| SCHEMBL14791222 | 0.85 | GRIN2B (0.35) | GPR119ADAM17MMP13STAT5B | |
| SCHEMBL4350480 | 0.84 | ALDH1A1 (0.37) | STAT3L3MBTL1STAT5BALDH1A1 | |
| SCHEMBL4354349 | 0.83 | L3MBTL1 (0.36) | L3MBTL1ALDH1A1 | |
| SCHEMBL23546231 | 0.81 | PIK3CD (0.36) | GPR119ADAM17MMP13STAT5B | |
| SCHEMBL29899353 | 0.81 | PIK3CD (0.36) | GPR119ADAM17MMP13STAT5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102118968-A | Novel tricyclic compounds | ABBOTT LAB | 2011-07-06 | — | — | CN | disclosed |