Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27797611 | 0.85 | PTGDR2 (0.30) | — | |
| SCHEMBL27799032 | 0.81 | GABRR1 (0.31) | GABRR1 | |
| SCHEMBL11312405 | 0.77 | — | — | |
| SCHEMBL27797900 | 0.73 | KDM4E (0.30) | — | |
| SCHEMBL8763542 | 0.72 | CYP1A2 (0.38) | GABRR1 | |
| SCHEMBL27820136 | 0.71 | — | — | |
| SCHEMBL10841293 | 0.68 | KDM4E (0.32) | — | |
| SCHEMBL27799018 | 0.68 | KDM4E (0.31) | — | |
| SCHEMBL27820175 | 0.64 | ALOX5 (0.34) | — | |
| SCHEMBL27709166 | 0.63 | ABCC8 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101891709-A | 5-halogenated methyl-1,2,3-thiadiazole compound and preparation method and use thereof | UNIV NANKAI | 2010-11-24 | — | — | CN | claimed |
| CN-101891709-B | 5-halogenated methyl-1,2,3-thiadiazole compound and preparation method and use thereof | UNIV NANKAI | 2012-11-21 | — | — | CN | disclosed |
| CN-101891709-A | 5-halogenated methyl-1,2,3-thiadiazole compound and preparation method and use thereof | UNIV NANKAI | 2010-11-24 | — | — | CN | disclosed |