Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 2/20 | 0.31 |
| ▸ | CNR2 | P34972 | 2/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.30 |
| ▸ | HRH2 | P25021 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27821973 | 0.86 | NOS2 (0.43) | TLR7NOS2DYRK1AADORA2AADORA2B | |
| SCHEMBL27841280 | 0.78 | TLR7 (0.37) | TLR7NOS2CDK9DYRK1ADYRK2 | |
| SCHEMBL28792136 | 0.77 | NOS2 (0.44) | TLR7NOS2ADORA2AADORA2BCNR1 | |
| SCHEMBL283715 | 0.76 | KDM4E (0.39) | CDK9DYRK1ADYRK2JAK2JAK1 | |
| SCHEMBL7272832 | 0.74 | NOS2 (0.44) | TLR7NOS2GABRA2GABRB2ADORA2A | |
| SCHEMBL28289187 | 0.72 | KDM4E (0.46) | GABRA2GABRB2 | |
| SCHEMBL22756710 | 0.72 | NOS2 (0.37) | TLR7NOS2GABRA2GABRB2CNR1 | |
| SCHEMBL27667658 | 0.72 | LMNA (0.40) | CNR1CNR2 | |
| SCHEMBL27836956 | 0.72 | NOS2 (0.40) | TLR7NOS2ADORA2AADORA2BCNR1 | |
| SCHEMBL10625859 | 0.71 | CNR1 (0.41) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102216277-A | Substituted benzamides as cannabinoid receptor ligands | ABBOTT LAB | 2011-10-12 | — | — | CN | disclosed |