Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.54 |
| ▸ | HPGD | P15428 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.50 |
| ▸ | FEN1 | P39748 | 1/20 | 0.50 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL606359 | 0.83 | KMT2A (0.49) | HSD17B10ALDH1A1KDM4EHPGDKMT2A | |
| SCHEMBL31231930 | 0.83 | KMT2A (0.49) | HSD17B10ALDH1A1KDM4EHPGDKMT2A | |
| SCHEMBL28780907 | 0.78 | KMT2A (0.51) | HSD17B10ALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL24453236 | 0.75 | ERCC1 (0.63) | HSD17B10ALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL28385189 | 0.74 | KCNH2 (0.37) | HSD17B10ALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL20735193 | 0.74 | ALDH1A1 (0.82) | HSD17B10ALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL29179695 | 0.72 | HSD17B10 (1.00) | HSD17B10ALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL28780761 | 0.72 | ALDH1A1 (0.49) | HSD17B10ALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL824432 | 0.72 | ALDH1A1 (0.62) | HSD17B10ALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL28517468 | 0.72 | ERCC1 (0.59) | HSD17B10ALDH1A1KDM4EHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116589493-A | Fluorescent probe based on mercapto naphthalimide and preparation method and application thereof | 山西大学 | 2023-08-15 | — | — | CN | claimed |
| CN-113121563-B | Thienophthalimide compound, thiophenethiol and preparation and application thereof | 北京化工大学 | 2022-10-28 | — | — | CN | disclosed |
| CN-113121563-B | Thienophthalimide compound, thiophenethiol and preparation and application thereof | 北京化工大学 | 2022-10-28 | — | — | CN | disclosed |
| CN-113912634-A | Bromination method of bilateral bithiophene thick naphthalimide and brominated product | 北京化工大学 | 2022-01-11 | — | — | CN | disclosed |
| CN-113121563-A | Thienophthalimide compound, thiophenethiol and preparation and application thereof | 北京化工大学 | 2021-07-16 | — | — | CN | disclosed |
| CN-112480376-A | N-type polymer semiconductor material, preparation method and application | 苏州大学 | 2021-03-12 | — | — | CN | disclosed |
| CN-101941984-B | 2,1, 3-thiadiazole naphthalimide compound and application thereof in tumor cells | UNIV DALIAN TECH | 2012-07-25 | — | — | CN | disclosed |
| CN-101941984-A | 2,1, 3-thiadiazole naphthalimide compound and application thereof in tumor cells | UNIV DALIAN TECH | 2011-01-12 | — | — | CN | disclosed |