Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | GPR183 | P32249 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27730871 | 0.80 | NAMPT (0.38) | ALDH1A1LMNAHTT | |
| SCHEMBL18702163 | 0.79 | GPR183 (0.58) | ALDH1A1GPR183MAPTLMNA | |
| SCHEMBL710366 | 0.78 | TGM2 (0.64) | GPR183 | |
| SCHEMBL27859336 | 0.77 | DRD2 (0.48) | ALDH1A1GAAMAPTLMNASMN1; SMN2 | |
| SCHEMBL9344505 | 0.77 | ALDH1A1 (0.65) | ALDH1A1GPR183RAB9ALMNATSHR | |
| SCHEMBL31315858 | 0.77 | ALDH1A1 (0.65) | ALDH1A1GPR183RAB9ALMNATSHR | |
| SCHEMBL28144813 | 0.77 | ATM (0.47) | ALDH1A1MAPTTSHRSMN1; SMN2 | |
| SCHEMBL6977155 | 0.75 | TGM2 (0.62) | GPR183 | |
| SCHEMBL14490210 | 0.74 | TGM2 (0.59) | ALDH1A1GPR183 | |
| SCHEMBL27981787 | 0.74 | POLB (0.51) | ALDH1A1GPR183MAPTLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102216249-A | Naphthylacetic acids | HOFFMANN LA ROCHE | 2011-10-12 | — | — | CN | disclosed |