Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28195386 | 0.96 | ALDH1A1 (0.43) | GPR88PPARGPPARAALDH1A1KDM4E | |
| SCHEMBL28885400 | 0.82 | ALDH1A1 (0.51) | GPR88PPARGPPARAALDH1A1SMN1; SMN2 | |
| SCHEMBL13162403 | 0.81 | MAOA (0.53) | PPARGPPARAALDH1A1KDM4EHPGD | |
| SCHEMBL28196047 | 0.80 | ABL1 (0.35) | KDM4EHPGDL3MBTL1CYP1A2CYP2C19 | |
| SCHEMBL28365855 | 0.79 | ALDH1A1 (0.54) | ALDH1A1KDM4EHPGDCYP1A2CYP2C19 | |
| SCHEMBL13162398 | 0.78 | MAOA (0.59) | MAOAMAOB | |
| SCHEMBL13162399 | 0.77 | MAOA (0.49) | PPARGPPARAALDH1A1KDM4EHPGD | |
| SCHEMBL27139421 | 0.76 | PLA2G2A (0.48) | ALDH1A1KDM4EHPGDL3MBTL1SMN1; SMN2 | |
| SCHEMBL29938041 | 0.75 | MAPT (0.48) | ALDH1A1KDM4EL3MBTL1SMN1; SMN2CYP1A2 | |
| SCHEMBL2325264 | 0.75 | MAPT (0.48) | ALDH1A1KDM4EL3MBTL1SMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101981035-B | Salts of triazoles as PAR1 inhibitors, their preparation and their use as medicaments | SANOFI AVENTIS | 2013-08-28 | — | — | CN | disclosed |
| CN-101981034-B | Triazolopyridazines as PAR1 inhibitors, their preparation and their use for producing medicaments | SANOFI AVENTIS | 2013-08-14 | — | — | CN | disclosed |
| CN-101981034-A | Triazolopyridazines as PAR1 inhibitors, their preparation and their use as medicaments | SANOFI AVENTIS | 2011-02-23 | — | — | CN | disclosed |