SCHEMBL27824331

SCHEMBL27824331

CNC(=O)Oc1ccno1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.39
MAPK1 P28482 2/20 0.38
GAA P10253 2/20 0.38
ACHE P22303 2/20 0.38
PGR P06401 1/20 0.38
PTGS1 P23219 1/20 0.38
HSD17B10 Q99714 1/20 0.38
KMT2A Q03164 4/20 0.34
LMNA P02545 2/20 0.34
TAAR1 Q96RJ0 1/20 0.33
MEN1 O00255 2/20 0.33
KDM4E B2RXH2 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
NPC1 O15118 1/20 0.32
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
GFER P55789 1/20 0.32
BCHE P06276 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20855352 0.79
SCHEMBL203961 0.76
SCHEMBL10974401 0.76 TAAR1 (0.54) ALDH1A1GAAACHEKMT2ALMNA
SCHEMBL3380446 0.75
SCHEMBL9207655 0.75
SCHEMBL2014284 0.68 MMP1 (0.46) ALDH1A1MAPK1GAAACHEPGR
SCHEMBL353475 0.67
SCHEMBL27150841 0.67 ALDH1A1 (0.49) ALDH1A1MAPK1GAAACHEPGR
Benzene SCHEMBL9125805 0.67 MMP1 (0.45) ALDH1A1MAPK1GAAACHEPGR
SCHEMBL12893245 0.66 ALDH1A1 (0.51) ALDH1A1MAPK1GAAACHEPGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102333764-A Substituted azole derivatives, pharmaceutical composition containing the derivatives, and method for treating parkinson's disease using the same SK HOLDINGS CO LTD 2012-01-25 CN claimed