Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR3 | P22607 | 2/20 | 0.58 |
| ▸ | EGFR | P00533 | 1/20 | 0.53 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.51 |
| ▸ | CAMKK2 | Q96RR4 | 4/20 | 0.51 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.51 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.48 |
| ▸ | AURKA | O14965 | 2/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2322576 | 0.81 | EPHB4 (0.59) | FGFR3EGFRPIK3CGAURKAKDR | |
| SCHEMBL2327107 | 0.81 | FGFR2 (0.56) | FGFR3EGFRPIK3CGKMT2AKDR | |
| SCHEMBL2326760 | 0.79 | CDK1 (0.51) | FGFR3EGFRMAPK10CAMKK2MAPK8 | |
| SCHEMBL2330210 | 0.78 | TBK1 (0.51) | FGFR3EGFRPIK3CGMAPTKDM4E | |
| SCHEMBL2327161 | 0.76 | CDK4 (0.40) | FGFR3CAMKK2SMN1; SMN2AURKAKDR | |
| SCHEMBL2323002 | 0.76 | CDK1 (0.41) | PIK3CGSMN1; SMN2AURKAKDRGSK3B | |
| SCHEMBL2327157 | 0.74 | SMN1; SMN2 (0.50) | EGFRMAPK10MAPTALDH1A1KMT2A | |
| SCHEMBL2325853 | 0.74 | CDK1 (0.50) | FGFR3EGFRPIK3CGMAPTKDR | |
| SCHEMBL2323093 | 0.74 | KMT2A (0.45) | MAPK10MAPK8MAPTKDM4EALDH1A1 | |
| SCHEMBL2330481 | 0.74 | KDR (0.46) | FGFR3KDRFGFR2GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102239160-A | Substituted (pyridyl) -azinylamine derivatives as fungicides | BAYER CROPSCIENCE SA | 2011-11-09 | — | — | CN | claimed |
| CN-102239160-A | Substituted (pyridyl) -azinylamine derivatives as fungicides | BAYER CROPSCIENCE SA | 2011-11-09 | — | — | CN | disclosed |