Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | CTSC | P53634 | 1/20 | 0.37 |
| ▸ | GHSR | Q92847 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28270587 | 0.92 | TSHR (0.46) | TSHRPOLBHTR2CHTR2BGLA | |
| SCHEMBL27664302 | 0.85 | POLB (0.43) | TSHRPOLBHTR2CHTR2BLTA4H | |
| SCHEMBL27843143 | 0.85 | HTR2C (0.42) | TSHRPOLBHTR2CHTR2BLTA4H | |
| SCHEMBL28238992 | 0.82 | TSHR (0.48) | TSHRPOLBHTR2CGLA | |
| Azetidine SCHEMBL27976635 | 0.82 | TSHR (0.41) | TSHRHTR2C | |
| SCHEMBL27772138 | 0.82 | TSHR (0.43) | TSHRPOLBHTR2C | |
| SCHEMBL28776632 | 0.82 | POLB (0.52) | TSHRPOLBLTA4HGHSR | |
| SCHEMBL27879042 | 0.82 | CTSC (0.41) | TSHRPOLBHTR2CHTR2BLTA4H | |
| SCHEMBL27939939 | 0.81 | TSHR (0.42) | TSHRHTR2CLTA4HGLA | |
| SCHEMBL28274307 | 0.81 | TSHR (0.42) | TSHRHTR2CLTA4HGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101998959-B | Benzoxazole carboxamide inhibitors of poly(ADP-ribose)polymerase (PARP) | BIOMARIN PHARM INC | 2013-08-28 | — | — | CN | disclosed |
| CN-101998959-A | Benzoxazole carboxamide inhibitors of poly(ADP-ribose)polymerase (PARP) | LEAD THERAPEUTICS INC | 2011-03-30 | — | — | CN | disclosed |