Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 11/20 | 0.37 |
| ▸ | G6PD | P11413 | 1/20 | 0.36 |
| ▸ | IDE | P14735 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5700283 | 0.81 | ROCK1 (0.37) | G6PDIDEROCK1 | |
| SCHEMBL3465117 | 0.81 | LMNA (0.35) | HRH4ROCK1 | |
| SCHEMBL1707627 | 0.71 | UHRF1 (0.48) | — | |
| SCHEMBL13801171 | 0.71 | UHRF1 (0.48) | G6PDIDEROCK1 | |
| SCHEMBL10920036 | 0.71 | ROCK1 (0.40) | G6PDIDEROCK1 | |
| SCHEMBL22601560 | 0.70 | HRH4 (0.36) | HRH4ROCK1 | |
| SCHEMBL6883165 | 0.69 | PTGS2 (0.46) | ROCK1 | |
| SCHEMBL1403910 | 0.69 | PTGS1 (0.39) | G6PDIDEROCK1 | |
| SCHEMBL31599666 | 0.69 | PTGS1 (0.39) | G6PDIDEROCK1 | |
| SCHEMBL30700822 | 0.69 | PTGS2 (0.46) | ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102227425-A | Azaindazole compounds as ccr1 receptor antagonists | BOEHRINGER INGELHEIM INT | 2011-10-26 | — | — | CN | disclosed |