Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | G6PD | P11413 | 1/20 | 0.36 |
| ▸ | IDE | P14735 | 1/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1403910 | 1.00 | PTGS1 (0.39) | PTGS1PTGS2ROCK1SMN1; SMN2G6PD | |
| SCHEMBL24669127 | 0.79 | CA2 (0.48) | ROCK1LMNAHTR6 | |
| SCHEMBL28157668 | 0.79 | ALDH1A1 (0.39) | SMN1; SMN2ARLMNAHTR6 | |
| SCHEMBL17694102 | 0.79 | HRH4 (0.38) | SMN1; SMN2HTR6 | |
| SCHEMBL10920036 | 0.77 | ROCK1 (0.40) | PTGS1PTGS2ROCK1SMN1; SMN2G6PD | |
| SCHEMBL13801171 | 0.77 | UHRF1 (0.48) | PTGS2ROCK1SMN1; SMN2G6PDIDE | |
| SCHEMBL5700299 | 0.76 | SMN1; SMN2 (0.50) | ROCK1SMN1; SMN2METLMNA | |
| SCHEMBL30700822 | 0.75 | PTGS2 (0.46) | PTGS1PTGS2ROCK1LMNA | |
| SCHEMBL16289399 | 0.75 | ROCK1 (0.39) | PTGS1PTGS2ROCK1SMN1; SMN2G6PD | |
| SCHEMBL6883165 | 0.75 | PTGS2 (0.46) | PTGS1PTGS2ROCK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025111251-A1 | COMPOUNDS THAT INHIBIT POLO-LIKE KINASE 4 | EXELIXIS, INC. (US) | 2025-05-30 | — | — | WO | disclosed |