Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.38 |
| ▸ | CA2 | P00918 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 3/20 | 0.33 |
| ▸ | CA9 | Q16790 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6754107 | 0.72 | LMNA (0.43) | POLBMAPTPKMLMNAALDH1A1 | |
| SCHEMBL28016208 | 0.71 | LMNA (0.38) | POLBMAPTPKMPTGS2CA2 | |
| SCHEMBL27487969 | 0.71 | KMT2A (0.44) | POLBMAPTPKMLMNAALDH1A1 | |
| SCHEMBL1249499 | 0.71 | KDM4E (0.39) | POLBMAPTPKMLMNAALDH1A1 | |
| SCHEMBL27523196 | 0.71 | KDM4E (0.38) | POLBMAPTPKMPTGS2LMNA | |
| SCHEMBL12319524 | 0.71 | ALDH1A1 (0.44) | POLBMAPTPKMLMNAALDH1A1 | |
| SCHEMBL14030826 | 0.70 | ALDH1A1 (0.47) | POLBPTGS2CA2LMNAALDH1A1 | |
| SCHEMBL27839207 | 0.69 | LMNA (0.36) | POLBMAPTPKMPTGS2LMNA | |
| SCHEMBL6229622 | 0.69 | TDP1 (0.51) | POLBMAPTPTGS2LMNAALDH1A1 | |
| SCHEMBL27858874 | 0.68 | ALDH1A1 (0.41) | POLBMAPTPTGS2LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102227425-A | Azaindazole compounds as ccr1 receptor antagonists | BOEHRINGER INGELHEIM INT | 2011-10-26 | — | — | CN | disclosed |