SCHEMBL27827367

SCHEMBL27827367

CC[SiH](CCO)OCc1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.39
TSHR P16473 3/20 0.39
TDP1 Q9NUW8 3/20 0.38
CYP4F2 P78329 1/20 0.37
CYP4A11 Q02928 1/20 0.37
LTA4H P09960 1/20 0.37
EPHX2 P34913 1/20 0.37
IDO1 P14902 1/20 0.36
TP53 P04637 1/20 0.35
AGXT P21549 1/20 0.35
SLC6A2 P23975 2/20 0.35
SLC6A3 Q01959 2/20 0.35
LMNA P02545 1/20 0.35
CYP1A2 P05177 1/20 0.35
PTGS1 P23219 1/20 0.35
CYP2C19 P33261 1/20 0.35
PTGS2 P35354 1/20 0.35
HIF1A Q16665 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35
NR4A1 P22736 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3482440 0.85 TSHR (0.41) ALDH1A1TSHRTDP1IDO1TP53
SCHEMBL704328 0.85 TSHR (0.48) ALDH1A1TSHRTDP1IDO1TP53
SCHEMBL3481604 0.82 CETP (0.41) ALDH1A1TSHRTDP1IDO1TP53
SCHEMBL11418607 0.82 TSHR (0.39) ALDH1A1TSHRTDP1IDO1TP53
SCHEMBL27806779 0.78 TSHR (0.41) ALDH1A1TSHRTDP1CYP4F2CYP4A11
SCHEMBL703243 0.77 TSHR (0.44) ALDH1A1TSHRTDP1IDO1TP53
SCHEMBL706931 0.74 CETP (0.42) ALDH1A1TSHRTDP1IDO1TP53
SCHEMBL18297920 0.72 TSHR (0.48) ALDH1A1TSHRTDP1IDO1TP53
SCHEMBL10568560 0.71 TSHR (0.46) ALDH1A1TSHRTDP1IDO1TP53
Propanol SCHEMBL1756185 0.69 TSHR (0.68) ALDH1A1TSHRTDP1CYP4F2CYP4A11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102746467-B Curable composition and process for production of organosilicon compound TOAGOSEI CO LTD 2015-01-14 CN disclosed
CN-101981087-B Curable composition and method for producing organosilicon compound TOAGOSEI CO LTD 2012-11-21 CN disclosed
CN-102746467-A Curable composition and process for production of organosilicon compound TOAGOSEI CO LTD 2012-10-24 CN disclosed
CN-101981087-A Curable composition and method for producing organosilicon compound TOAGOSEI CO LTD 2011-02-23 CN disclosed