SCHEMBL704328

SCHEMBL704328

CC[SiH](CC)OCc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.48
IDO1 P14902 1/20 0.44
TP53 P04637 1/20 0.44
AGXT P21549 1/20 0.43
ALDH1A1 P00352 3/20 0.42
MAPT P10636 1/20 0.41
MAPK1 P28482 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA9 Q16790 1/20 0.38
LMNA P02545 1/20 0.38
CYP1A2 P05177 1/20 0.38
PTGS1 P23219 1/20 0.38
SLC6A2 P23975 1/20 0.38
CYP2C19 P33261 1/20 0.38
PTGS2 P35354 1/20 0.38
SLC6A3 Q01959 1/20 0.38
HIF1A Q16665 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3482440 0.88 TSHR (0.41) TSHRIDO1TP53AGXTALDH1A1
SCHEMBL3481604 0.85 CETP (0.41) TSHRIDO1TP53AGXTALDH1A1
SCHEMBL11418607 0.85 TSHR (0.39) TSHRIDO1TP53AGXTALDH1A1
SCHEMBL27827367 0.85 ALDH1A1 (0.39) TSHRIDO1TP53AGXTALDH1A1
SCHEMBL703243 0.83 TSHR (0.44) TSHRIDO1TP53AGXTALDH1A1
SCHEMBL18297920 0.82 TSHR (0.48) TSHRIDO1TP53AGXTALDH1A1
SCHEMBL10568560 0.80 TSHR (0.46) TSHRIDO1TP53AGXTALDH1A1
SCHEMBL28719483 0.80 AGXT (0.50) IDO1AGXTALDH1A1MAPTMAPK1
SCHEMBL706931 0.79 CETP (0.42) TSHRIDO1TP53AGXTALDH1A1
SCHEMBL704244 0.78 TDP1 (0.43) IDO1TP53ALDH1A1TDP1CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115181223-B Low-gloss matte auxiliary agent, preparation method thereof and molded body 铨盛聚碳科技股份有限公司 2023-08-29 CN claimed
US-20100137525-A1 Catalyst composition for hydrogenation and their use for hydrogenation conjugated diene polymer CHI-MEI CORPORATION 2010-06-03 US claimed
US-20080171653-A1 Catalyst composition for hydrogenation and their use for hydrogenation conjugated diene polymer CHI-MEI CORPORATION 2008-07-17 US claimed
CN-1324867-A Catalyst composition for hydrogenation of conjugated diene polymer and process for hydrogenation of the polymer INST OF IND TECHN (CN) 2001-12-05 CN claimed
US-6313230-B1 HYDROGENATING CONJUGATED DIENE POLYMERS IN PRESENCE OF HYDROGEN AND A HYDROGENATION CATALYST FORMULATION COMPRISING TITANIUM COMPOUND, SILYL HYDRIDE COMPOUND, POLYSILOXANE, SILAZAN COMPOUND, AND METALLIC COMPOUND INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2001-11-06 US claimed
WO-2024176969-A1 METHOD FOR PRODUCING CARBONIC ACID DIESTER 国立研究開発法人産業技術総合研究所 2024-08-29 WO disclosed
CN-115181223-B Low-gloss matte auxiliary agent, preparation method thereof and molded body 铨盛聚碳科技股份有限公司 2023-08-29 CN disclosed
EP-4056604-B1 METHOD FOR PRODUCING COPOLYMER OF 1,3,7-OCTATRIENE AND STYRENE KURARAY CO (JP) 2023-08-02 EP disclosed
EP-3564280-B1 COPOLYMER OF 1, 3, 7-OCTATRIENE AND STYRENE AND HYDRIDE THEREOF KURARAY CO (JP) 2023-07-26 EP disclosed
EP-4163311-A1 COPOLYMER OF 1,3,7-OCTATRIENE AND ISOPRENE, HYDRIDE THEREOF, AND METHOD FOR PRODUCING SAID COPOLYMER Kuraray Co., Ltd. (JP) 2023-04-12 EP disclosed
EP-4163312-A1 COPOLYMER OF 1,3,7-OCTATRIENE AND ISOPRENE, HYDRIDE THEREOF, AND METHOD FOR PRODUCING SAID COPOLYMER Kuraray Co., Ltd. (JP) 2023-04-12 EP disclosed
EP-3564274-B1 1, 3, 7-OCTATRIENE POLYMER, HYDRIDE THEREOF, AND METHOD FOR PRODUCING SAID POLYMER KURARAY CO (JP) 2022-12-28 EP disclosed
US-20080262161-A1 Apparatus for hydrogenation and method for hydrogenating conjugated diene polymer by employing the apparatus CHI-MEI CORPORATION 2008-10-23 US disclosed
CN-101249457-A Hydrogenation catalyst composition and use thereof for hydrogenation of conjugated diene polymer CHI MEI IND CO LTD (CN) 2008-08-27 CN disclosed
US-20080171653-A1 Catalyst composition for hydrogenation and their use for hydrogenation conjugated diene polymer CHI-MEI CORPORATION 2008-07-17 US disclosed
CN-1930175-A Compositions for treating and/or preventing diseases characterized by the presence of metal ions GRENPHARMA LLC (US) 2007-03-14 CN disclosed
US-20070026689-A1 Silica film forming material, silica film and method of manufacturing the same, multilayer wiring structure and method of manufacturing the same, and semiconductor device and method of manufacturing the same FUJITSU LIMITED (JP) 2007-02-01 US disclosed
CN-1130382-C Catalyst composition for hydrogenation of conjugated diene polymer and process for hydrogenation of the polymer INST IND TECHNOLOGY (CN) 2003-12-10 CN disclosed
CN-1324867-A Catalyst composition for hydrogenation of conjugated diene polymer and process for hydrogenation of the polymer INST OF IND TECHN (CN) 2001-12-05 CN disclosed
US-6313230-B1 HYDROGENATING CONJUGATED DIENE POLYMERS IN PRESENCE OF HYDROGEN AND A HYDROGENATION CATALYST FORMULATION COMPRISING TITANIUM COMPOUND, SILYL HYDRIDE COMPOUND, POLYSILOXANE, SILAZAN COMPOUND, AND METALLIC COMPOUND INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2001-11-06 US disclosed