Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.51 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9464864 | 0.83 | MEN1 (0.54) | MEN1KMT2ASMN1; SMN2CYP19A1TBXAS1 | |
| SCHEMBL28287055 | 0.81 | IDO1 (0.66) | MEN1KMT2ACYP19A1MAPK1HSD17B10 | |
| SCHEMBL5229864 | 0.74 | CAMK2D (0.59) | GSK3BQPCTSIRT2 | |
| SCHEMBL28663094 | 0.73 | CYP3A4 (0.49) | MEN1KMT2ASMN1; SMN2CYP19A1TBXAS1 | |
| SCHEMBL5682674 | 0.72 | SIRT2 (0.64) | MEN1KMT2ASMN1; SMN2CYP19A1TBXAS1 | |
| SCHEMBL16382293 | 0.72 | IDO1 (0.73) | MEN1KMT2ACYP19A1MAPK1IDO1 | |
| SCHEMBL31408101 | 0.72 | IDO1 (0.73) | MEN1KMT2ACYP19A1MAPK1IDO1 | |
| SCHEMBL1202543 | 0.72 | IMPDH2 (0.63) | MEN1KMT2ASMN1; SMN2MAPK1IMPDH2 | |
| SCHEMBL27747140 | 0.72 | IDO1 (0.54) | MEN1KMT2ASMN1; SMN2CYP19A1MAPK1 | |
| SCHEMBL29852234 | 0.72 | MEN1 (0.58) | MEN1KMT2ACYP19A1MAPK1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101959884-B | 6-heterocyclic imidazo [1,2-a ] pyridine-2-carboxamide derivatives, preparation and therapeutic use thereof | SANOFI AVENTIS | 2013-02-27 | — | — | CN | claimed |
| CN-101959884-A | 6-heterocyclic imidazo [1, 2-alpha ] pyridine-2-carboxamide derivatives, preparation and therapeutic use thereof | SANOFI AVENTIS | 2011-01-26 | — | — | CN | claimed |
| CN-101959884-B | 6-heterocyclic imidazo [1,2-a ] pyridine-2-carboxamide derivatives, preparation and therapeutic use thereof | SANOFI AVENTIS | 2013-02-27 | — | — | CN | disclosed |
| CN-101959884-A | 6-heterocyclic imidazo [1, 2-alpha ] pyridine-2-carboxamide derivatives, preparation and therapeutic use thereof | SANOFI AVENTIS | 2011-01-26 | — | — | CN | disclosed |