Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK2D | Q13557 | 6/20 | 0.59 |
| ▸ | PRKCB | P05771 | 3/20 | 0.59 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.59 |
| ▸ | CDK4 | P11802 | 2/20 | 0.59 |
| ▸ | PRKACA | P17612 | 2/20 | 0.59 |
| ▸ | PRKACG | P22612 | 2/20 | 0.59 |
| ▸ | PRKACB | P22694 | 2/20 | 0.59 |
| ▸ | CCND1 | P24385 | 2/20 | 0.59 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.59 |
| ▸ | CDK2 | P24941 | 2/20 | 0.59 |
| ▸ | PRKCA | P17252 | 2/20 | 0.59 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.59 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.59 |
| ▸ | ABL1 | P00519 | 1/20 | 0.59 |
| ▸ | PRKCG | P05129 | 1/20 | 0.59 |
| ▸ | CDK1 | P06493 | 1/20 | 0.59 |
| ▸ | PIM1 | P11309 | 1/20 | 0.59 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.59 |
| ▸ | PRKCH | P24723 | 1/20 | 0.59 |
| ▸ | PRKCI | P41743 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5682674 | 0.81 | SIRT2 (0.64) | CAMK2DPRKCBCCNE2CDK4PRKACA | |
| Ro-316233 SCHEMBL624896 | 0.77 | PRKCB (1.00) | CAMK2DPRKCBCCNE2CDK4PRKACA | |
| Ro-316233 SCHEMBL29373011 | 0.77 | PRKCB (1.00) | CAMK2DPRKCBCCNE2CDK4PRKACA | |
| SCHEMBL13917970 | 0.76 | PRKCB (0.78) | CAMK2DPRKCBCCNE2CDK4PRKACA | |
| SCHEMBL27827559 | 0.74 | MEN1 (0.51) | SIRT2GSK3BQPCT | |
| SCHEMBL5686122 | 0.74 | GSK3B (0.74) | CAMK2DPRKCBCCNE2CDK4PRKACA | |
| SCHEMBL5946249 | 0.73 | GSK3B (0.71) | CAMK2DPRKCBCCNE2CDK4PRKACA | |
| SCHEMBL9464864 | 0.71 | MEN1 (0.54) | PIM1 | |
| SCHEMBL7003063 | 0.71 | PRKCB (0.63) | CAMK2DPRKCBCCNE2CDK4PRKACA | |
| SCHEMBL13596802 | 0.70 | PRKCB (0.72) | CAMK2DPRKCBCCNE2CDK4PRKACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1070068-B2 | GRANULATIMIDE DERIVATIVES FOR USE IN CANCER TREATMENT | UNIV BRITISH COLUMBIA (CA) | 2007-01-17 | — | — | EP | disclosed |
| EP-1070068-B1 | GRANULATIMIDE DERIVATIVES FOR USE IN CANCER TREATMENT | UNIV BRITISH COLUMBIA (CA) | 2003-10-08 | — | — | EP | disclosed |
| US-6291447-B1 | INHIBITING THE G2 CHECKPOINT IN A CELL | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2001-09-18 | — | — | US | disclosed |
| EP-1070068-A1 | GRANULATIMIDE DERIVATIVES FOR USE IN CANCER TREATMENT | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2001-01-24 | — | — | EP | disclosed |
| WO-1999047522-A1 | GRANULATIMIDE DERIVATIVES FOR USE IN CANCER TREATMENT | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 1999-09-23 | — | — | WO | disclosed |