Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.63 |
| ▸ | SYK | P43405 | 11/20 | 0.55 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.53 |
| ▸ | INCENP | Q9NQS7 | 2/20 | 0.53 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4314016 | 0.89 | SYK (0.58) | PARP10SYKAURKBINCENPLMNA | |
| SCHEMBL30151716 | 0.85 | SYK (0.45) | PARP10SYKBRD4LMNAHTT | |
| SCHEMBL4319936 | 0.85 | SYK (0.56) | PARP10SYKAURKBINCENPBRD4 | |
| SCHEMBL2744895 | 0.81 | PARP10 (0.59) | PARP10LMNAHTTRAB9A | |
| SCHEMBL30765139 | 0.80 | PARP10 (0.68) | PARP10LMNAHTTRAB9A | |
| SCHEMBL29963339 | 0.79 | SYK (0.65) | SYKAURKBINCENPFFAR1 | |
| SCHEMBL6068690 | 0.79 | SYK (0.65) | SYKAURKBINCENPFFAR1 | |
| SCHEMBL6682997 | 0.77 | PARP10 (1.00) | PARP10 | |
| SCHEMBL29195674 | 0.76 | CCR5 (0.51) | SYKAURKBINCENPFFAR1 | |
| SCHEMBL30686435 | 0.76 | SLC6A4 (0.57) | SYKAURKBINCENPRAB9AFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102056594-B | Pharmaceutical depot comprising N-{5-[(cyclopropylamino)carbonyl]-2-methylphenyl}-3-fluoro-4-(pyridin-2-ylmethoxy)benzamide | ASTRAZENECA AB | 2013-06-12 | — | — | CN | disclosed |
| CN-102056594-A | Pharmaceutical depot comprising N-{5-[(cyclopropylamino)carbonyl]-2-methylphenyl}-3-fluoro-4-(pyridin-2-ylmethoxy)benzamide | ASTRAZENECA AB | 2011-05-11 | — | — | CN | disclosed |