Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.65 |
| ▸ | NPC1 | O15118 | 6/20 | 0.65 |
| ▸ | RAB9A | P51151 | 5/20 | 0.65 |
| ▸ | TP53 | P04637 | 4/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | GFER | P55789 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.62 |
| ▸ | HPGD | P15428 | 5/20 | 0.62 |
| ▸ | MEN1 | O00255 | 5/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | F2 | P00734 | 1/20 | 0.62 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1129179 | 1.00 | KDM4E (0.65) | KDM4EHSD17B10NPC1RAB9ATP53 | |
| SCHEMBL25027923 | 0.84 | KDM4E (0.71) | KDM4EHSD17B10NPC1RAB9ATP53 | |
| SCHEMBL29531707 | 0.80 | NPC1 (0.69) | KDM4EHSD17B10NPC1RAB9ATP53 | |
| SCHEMBL824375 | 0.80 | NPC1 (0.69) | KDM4EHSD17B10NPC1RAB9ATP53 | |
| SCHEMBL39752 | 0.79 | NPC1 (0.55) | KDM4EHSD17B10NPC1RAB9ATP53 | |
| SCHEMBL29392124 | 0.79 | NPC1 (0.55) | KDM4EHSD17B10NPC1RAB9ATP53 | |
| SCHEMBL12501435 | 0.79 | KDM4E (0.78) | KDM4EHSD17B10NPC1RAB9ATP53 | |
| SCHEMBL30851241 | 0.79 | KDM4E (0.69) | KDM4EHSD17B10NPC1RAB9ATP53 | |
| SCHEMBL2245749 | 0.79 | KDM4E (0.69) | KDM4EHSD17B10NPC1RAB9ATP53 | |
| SCHEMBL915809 | 0.78 | ALDH1A1 (0.61) | KDM4EHSD17B10NPC1RAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101056942-B | Flame retardant thermoplastic polycarbonate compositions, use thereof and method of its manufacture | GEN ELECTRIC | 2011-03-23 | — | — | CN | disclosed |