Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | DAO | P14920 | 2/20 | 0.45 |
| ▸ | UCHL5 | Q9Y5K5 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2739317 | 0.85 | HPGD (0.76) | HPGDADRA2CMAOAADRA1ADRD3 | |
| SCHEMBL3175959 | 0.84 | LMNA (0.48) | HPGDADRA2CMAOAADRA1ADRD3 | |
| SCHEMBL2141423 | 0.84 | DAO (0.64) | HPGDADRA2CMAOAADRA1ADRD3 | |
| SCHEMBL280104 | 0.83 | F2 (0.52) | HPGDADRA2CMAOAADRA1ADRD3 | |
| SCHEMBL22685732 | 0.81 | DAO (0.46) | HPGDADRA2CMAOAADRA1ADRD3 | |
| SCHEMBL2403566 | 0.79 | NPSR1 (0.53) | HPGDADRA2CMAOAADRA1ADRD3 | |
| SCHEMBL22685533 | 0.79 | DAO (0.40) | HPGDADRA2CMAOAADRA1ADRD3 | |
| SCHEMBL14072918 | 0.79 | KDM4E (0.50) | HPGDADRA2CMAOAADRA1ADRD3 | |
| SCHEMBL12789017 | 0.78 | ALDH1A1 (0.45) | HPGDADRA2CMAOAADRA1ADRD3 | |
| SCHEMBL22733577 | 0.78 | ADRA2C (0.39) | HPGDADRA2CMAOAADRA1ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102083839-A | Compound (I) | ASTRAZENECA AB | 2011-06-01 | — | — | CN | disclosed |