SCHEMBL27830481

SCHEMBL27830481

NC1(N)C=CC(S(=O)(=O)Nc2ccccc2)=CC1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 3/20 0.43
IL1RN P18510 1/20 0.43
ERAP1 Q9NZ08 1/20 0.43
KMT2A Q03164 3/20 0.41
MEN1 O00255 2/20 0.41
PKM P14618 2/20 0.41
ALDH1A1 P00352 1/20 0.41
CA2 P00918 4/20 0.41
CA1 P00915 3/20 0.41
POLB P06746 1/20 0.39
CA12 O43570 3/20 0.38
CA9 Q16790 3/20 0.38
MAPT P10636 1/20 0.38
MAPK1 P28482 1/20 0.38
HTT P42858 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
TMPRSS6 Q8IU80 2/20 0.37
HTR6 P50406 1/20 0.36
PGR P06401 1/20 0.36
BRD4 O60885 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18570260 0.82 KEAP1 (0.43) KEAP1IL1RNERAP1KMT2AMEN1
SCHEMBL21753683 0.79 KEAP1 (0.41) KEAP1IL1RNERAP1KMT2AMEN1
SCHEMBL23042949 0.79 KEAP1 (0.41) KEAP1IL1RNERAP1KMT2AMEN1
SCHEMBL27558814 0.76 KEAP1 (0.38) KEAP1IL1RNERAP1KMT2AMEN1
SCHEMBL28134926 0.76 KEAP1 (0.38) KEAP1IL1RNERAP1KMT2AMEN1
SCHEMBL3462879 0.73
SCHEMBL7117901 0.71 KEAP1 (0.48) KEAP1IL1RNERAP1KMT2AMEN1
Dimethyl Sulfone SCHEMBL29171468 0.67 PTGS2 (0.38) KMT2AMEN1ALDH1A1CA2CA1
SCHEMBL1120013 0.64 TAAR1 (0.34) ALDH1A1MAPTMAPK1HTT
Benzene SCHEMBL28178850 0.64 TAAR1 (0.34) ALDH1A1MAPTMAPK1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118027412-A Photo-alignment material 罗利克技术有限公司 2024-05-14 CN disclosed
CN-108912011-B Photoalignment material 罗立克科技股份公司 2021-09-24 CN disclosed
CN-109804306-A Light orientation copolymer material 罗利克技术有限公司 2019-05-24 CN disclosed
CN-108350174-A Photo-alignment material 罗利克技术有限公司 2018-07-31 CN disclosed
CN-108350363-A Can photo-alignment material composition 罗利克技术有限公司 2018-07-31 CN disclosed
CN-105733606-B Photoalignment composition 罗利克有限公司 2018-04-03 CN disclosed
CN-105733606-A Photoalignment Composition 罗利克有限公司 2016-07-06 CN disclosed
CN-101903494-B Photoalignment composition ROLIC AG (CH) 2016-03-02 CN disclosed
CN-101903494-A Photoalignment composition ROLIC LTD 2010-12-01 CN disclosed