Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 3/20 | 0.41 |
| ▸ | IL1RN | P18510 | 1/20 | 0.41 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 4/20 | 0.40 |
| ▸ | CA9 | Q16790 | 4/20 | 0.40 |
| ▸ | CA2 | P00918 | 4/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18570260 | 0.85 | KEAP1 (0.43) | KEAP1IL1RNERAP1CA12CA9 | |
| SCHEMBL23042949 | 0.83 | KEAP1 (0.41) | KEAP1IL1RNERAP1CA12CA9 | |
| SCHEMBL28134926 | 0.82 | KEAP1 (0.38) | KEAP1IL1RNERAP1CA12CA9 | |
| SCHEMBL27830481 | 0.79 | KEAP1 (0.43) | KEAP1IL1RNERAP1CA12CA9 | |
| SCHEMBL27558814 | 0.77 | KEAP1 (0.38) | KEAP1IL1RNERAP1CA12CA9 | |
| SCHEMBL19264995 | 0.72 | — | — | |
| SCHEMBL27936506 | 0.71 | POLB (0.37) | KMT2AMEN1PKMALDH1A1GAA | |
| SCHEMBL7117901 | 0.69 | KEAP1 (0.48) | KEAP1IL1RNERAP1CA12CA9 | |
| SCHEMBL27237934 | 0.67 | HTR6 (0.47) | KMT2AMEN1PKMALDH1A1POLB | |
| SCHEMBL7427190 | 0.65 | RARA (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020039601-A1 | OIL-IN-WATER TYPE EMULSION OF ACTINIC-RAY-CURABLE RESIN COMPOSITION, AND THERMAL RECORDING MATERIAL | 日本化薬株式会社 | 2020-02-27 | — | — | WO | disclosed |
| CN-106496373-B | Catalytic component and its preparation and application for olefinic polymerization | 中国石油化工股份有限公司 | 2019-09-27 | — | — | CN | disclosed |