Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | CBS | P35520 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27974387 | 0.86 | CYP19A1 (0.47) | ALOX15ALOX12CYP19A1CYP1A1CYP1A2 | |
| SCHEMBL4758966 | 0.85 | KMT2A (0.40) | ALOX15ALOX12CYP19A1CYP1A1CYP1A2 | |
| SCHEMBL7200862 | 0.85 | CYP1A1 (0.54) | ALOX15ALOX12CYP19A1CYP1A1CYP1A2 | |
| SCHEMBL27775453 | 0.81 | NPC1 (0.44) | ALOX12CYP19A1CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL3368235 | 0.81 | CYP19A1 (0.53) | CYP19A1CYP1A1CYP1A2CYP1B1MAPT | |
| SCHEMBL6723902 | 0.80 | CYP3A4 (0.55) | CYP19A1LMNACYP3A4MAPK1ALDH1A1 | |
| SCHEMBL28552152 | 0.79 | NPC1 (0.55) | CYP19A1POLBKMT2AMAPTRECQL | |
| SCHEMBL3364490 | 0.78 | ABCG2 (0.54) | CYP19A1MAPTCYP3A4MAPK1ALDH1A1 | |
| SCHEMBL6503937 | 0.77 | CYP19A1 (0.49) | ALOX15CYP19A1POLBKMT2AMAPT | |
| SCHEMBL5085611 | 0.77 | CYP3A4 (0.49) | CYP19A1CYP1A1CYP1A2CYP1B1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102344454-B | Wikstroemia indica (L.) C.A.Mey extract as well as preparation method and application thereof | UNIV GUANGDONG PHARM | 2013-11-06 | — | — | CN | disclosed |
| CN-102344454-A | Wikstroemia indica (L.) C.A.Mey extract as well as preparation method and application thereof | UNIV GUANGDONG PHARM | 2012-02-08 | — | — | CN | disclosed |