SCHEMBL6503937

SCHEMBL6503937

COc1cc(O)c2c(c1)OC(c1ccc(O)c(O)c1)C(=O)C2

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 3/20 0.49
ALDH1A1 P00352 3/20 0.46
MAPT P10636 3/20 0.46
ADORA3 P0DMS8 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
ATM Q13315 1/20 0.46
TAS2R31 P59538 1/20 0.46
ELAVL3 Q14576 1/20 0.43
ABCG2 Q9UNQ0 1/20 0.42
MMP2 P08253 2/20 0.41
MMP14 P50281 1/20 0.41
SYNJ2 O15056 1/20 0.41
BACE1 P56817 4/20 0.41
KDM4E B2RXH2 3/20 0.41
MEN1 O00255 2/20 0.41
GAA P10253 2/20 0.41
PKM P14618 2/20 0.41
KMT2A Q03164 2/20 0.41
HSD17B10 Q99714 2/20 0.41
APEX1 P27695 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14829729 0.92 CYP19A1 (0.52) CYP19A1ALDH1A1MAPTADORA3TDP1
SCHEMBL27974387 0.90 CYP19A1 (0.47) CYP19A1ALDH1A1MAPTADORA3TDP1
SCHEMBL3368235 0.90 CYP19A1 (0.53) CYP19A1ALDH1A1MAPTADORA3TDP1
SCHEMBL3364490 0.86 ABCG2 (0.54) CYP19A1ALDH1A1MAPTADORA3TDP1
SCHEMBL16151244 0.86 KDM4E (0.54) CYP19A1ALDH1A1MAPTADORA3TDP1
SCHEMBL8249167 0.86 KDM4E (0.54) CYP19A1ALDH1A1MAPTADORA3TDP1
SCHEMBL2781922 0.86 KDM4E (0.54) CYP19A1ALDH1A1MAPTADORA3TDP1
SCHEMBL7200862 0.84 CYP1A1 (0.54) CYP19A1ALDH1A1MAPTADORA3TDP1
SCHEMBL2319151 0.83 CYP19A1 (0.57) CYP19A1ALDH1A1MAPTATMTAS2R31
SCHEMBL6509060 0.82 CYP1A1 (0.56) CYP19A1ALDH1A1MAPTATMMMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12403124-B2 Central nervous system health supplement COE WILLIAM B (US) 2025-09-02 US disclosed
US-20220202766-A1 CENTRAL NERVOUS SYSTEM HEALTH SUPPLEMENT COE WILLIAM B (US) 2022-06-30 US disclosed
WO-2004041804-B1 TECHNICAL PROCESS FOR ISOLATING HOMOERIODICTYOL SYMRISE GMBH & CO KG (DE) 2005-01-27 WO disclosed
WO-2004041804-A3 TECHNICAL PROCESS FOR ISOLATING HOMOERIODICTYOL SYMRISE GMBH & CO KG (DE) 2004-12-09 WO disclosed
WO-2004041804-A2 TECHNICAL PROCESS FOR ISOLATING HOMOERIODICTYOL SYMRISE GMBH & CO. KG (DE) 2004-05-21 WO disclosed
WO-2004041804-A2 TECHNICAL PROCESS FOR ISOLATING HOMOERIODICTYOL SYMRISE GMBH & CO. KG (DE) 2004-05-21 WO disclosed