Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.40 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 6/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1034663 | 0.93 | SLC40A1 (0.45) | SLC40A1TYRO3XDHPTGES2CCNT1 | |
| SCHEMBL1035231 | 0.85 | SLC40A1 (0.44) | SLC40A1XDHPTGES2CCNT1CDK9 | |
| SCHEMBL1031607 | 0.85 | SLC40A1 (0.47) | SLC40A1XDHPTGES2CCNT1CDK9 | |
| SCHEMBL17772304 | 0.83 | KDM4E (0.37) | SLC40A1PIM1 | |
| SCHEMBL1035477 | 0.82 | SLC40A1 (0.40) | SLC40A1PTGES2IRAK4PIM1FYN | |
| SCHEMBL27830716 | 0.80 | SLC40A1 (0.40) | SLC40A1TYRO3PTGES2CCNT1CDK9 | |
| SCHEMBL17772310 | 0.76 | FABP1 (0.39) | CHRM3MMP2 | |
| SCHEMBL27830723 | 0.74 | SLC40A1 (0.37) | SLC40A1TYRO3PTGES2CCNT1CDK9 | |
| SCHEMBL1034313 | 0.69 | SLC40A1 (0.49) | SLC40A1PTGES2DYRK1A | |
| SCHEMBL1074809 | 0.68 | SLC40A1 (0.48) | SLC40A1XDHPTGES2DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102083438-A | Quenolines and related analogs as sirtuin modulators | SIRTRIS PHARMACEUTICALS INC | 2011-06-01 | — | — | CN | disclosed |