SCHEMBL27831721

SCHEMBL27831721

Cc1cc(C)cc(OB(O)O)c1.[LiH]

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.39
TSHR P16473 2/20 0.39
CYP3A4 P08684 1/20 0.39
MAPK1 P28482 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.37
NPSR1 Q6W5P4 1/20 0.33
TPMT P51580 1/20 0.32
TP53 P04637 1/20 0.32
ALOX15 P16050 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
POLB P06746 1/20 0.31
CYP2C9 P11712 1/20 0.31
PRSS1 P07477 1/20 0.31
PRSS2 P07478 1/20 0.31
C1S P09871 1/20 0.31
PRSS3 P35030 1/20 0.31
MAPT P10636 2/20 0.31
HPGD P15428 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4086875 0.97 ALDH1A1 (0.41) ALDH1A1TSHRCYP3A4MAPK1TDP1
SCHEMBL27811325 0.95 ALDH1A1 (0.39) ALDH1A1TSHRCYP3A4MAPK1TDP1
Ammonia Solution, Strong SCHEMBL29088797 0.95 ALDH1A1 (0.39) ALDH1A1TSHRCYP3A4MAPK1TDP1
SCHEMBL29706573 0.84 ALDH1A1 (0.33) ALDH1A1TSHRCYP3A4MAPK1TDP1
SCHEMBL22769689 0.84 ALDH1A1 (0.48) ALDH1A1CYP3A4ALOX15CYP2C9MAPT
SCHEMBL29112060 0.84 ALDH1A1 (0.33) ALDH1A1TSHRCYP3A4MAPK1TDP1
SCHEMBL31300184 0.82 RAPGEF4 (0.31) ALDH1A1TSHRCYP3A4MAPK1TDP1
SCHEMBL630367 0.82 ALDH1A1 (0.41) ALDH1A1TSHRCYP3A4MAPK1TDP1
Propylene Glycol SCHEMBL28899293 0.82 TDP1 (0.37) ALDH1A1TSHRCYP3A4MAPK1TDP1
SCHEMBL30532200 0.79 RXRA (0.37) ALDH1A1TSHRSMN1; SMN2POLBCYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1890270-B Catalyst composition for producing polyolefins in the absence of a cocatalyst CHEVRON PHILLIPS CHEMICAL CO 2011-06-01 CN disclosed