Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.44 |
| ▸ | HTR1A | P08908 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1959132 | 0.92 | KMT2A (0.44) | KMT2AGAAMEN1ALDH1A1MAPT | |
| SCHEMBL27831709 | 0.88 | CYP2C9 (0.45) | KMT2AMEN1ALDH1A1MAPTCYP2C9 | |
| SCHEMBL27831940 | 0.86 | HRH3 (0.49) | HRH3HTR1ACYP2C9CYP2C19DRD2 | |
| SCHEMBL27850269 | 0.84 | KMT2A (0.48) | KMT2AGAAMEN1ALDH1A1MAPT | |
| SCHEMBL1957648 | 0.82 | BCL2 (0.46) | HTR1AKDM4E | |
| SCHEMBL1958106 | 0.80 | BCL2 (0.44) | ALDH1A1KDM4E | |
| SCHEMBL1957122 | 0.79 | BCL2 (0.43) | — | |
| SCHEMBL1955331 | 0.79 | BCL2 (0.52) | — | |
| SCHEMBL27831837 | 0.78 | HTR1A (0.49) | GAAALDH1A1MAPTHRH3HTR1A | |
| SCHEMBL27850404 | 0.75 | BCL2 (0.51) | CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102307872-A | BCL-2-selectively apoptosis-inducing agents for the treatment of cancer and immune diseases | ABBOTT LAB | 2012-01-04 | — | — | CN | disclosed |