⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1783160 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL28312859 | 0.79 | RAB9A (0.44) | — | |
| SCHEMBL29793056 | 0.79 | KIF11 (0.60) | — | |
| SCHEMBL1368828 | 0.79 | KIF11 (0.60) | — | |
| SCHEMBL238813 | 0.75 | — | — | |
| SCHEMBL578708 | 0.75 | — | — | |
| SCHEMBL1013700 | 0.75 | — | — | |
| SCHEMBL22113986 | 0.75 | — | — | |
| SCHEMBL115502 | 0.75 | — | — | |
| SCHEMBL30212452 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102993250-B | -9-deoxidation-9A-azepine-9A-the a-homoerythromycin A derivatives that C-3 replaces | Luoyang Huizhong Animal Medicine Co., Ltd. (CN) | 2016-02-10 | — | — | CN | claimed |
| CN-103965273-A | Macrolide compound | PU LIKE BIO ENG CO LTD | 2014-08-06 | — | — | CN | claimed |
| CN-108059631-A | A kind of preparation method of PIM kinase inhibitors and its intermediate | 上海方予健康医药科技有限公司 | 2018-05-22 | — | — | CN | disclosed |
| CN-103159760-B | As the 7-azaindole derivatives of CFTR adjusting control agent | 沃泰克斯药物股份有限公司 | 2016-06-08 | — | — | CN | disclosed |
| CN-102993250-B | -9-deoxidation-9A-azepine-9A-the a-homoerythromycin A derivatives that C-3 replaces | Luoyang Huizhong Animal Medicine Co., Ltd. (CN) | 2016-02-10 | — | — | CN | disclosed |
| CN-105102456-A | Azaquinazoline inhibitors of atypical protein kinase C | IGNYTA INC | 2015-11-25 | — | — | CN | disclosed |
| CN-103347510-B | Lysophosphatidic acid receptor antagonists and their use in the treatment of fibrosis | AMIRA PHARMACEUTICALS, INC. (US) | 2015-11-25 | — | — | CN | disclosed |
| CN-102574845-B | 1H-imidazo [4,5-c] qualone derivative | NOVARTIS AG (CH) | 2015-09-02 | — | — | CN | disclosed |
| CN-102947292-B | nitrogen-containing heteroaryl compounds | HOFFMAN-LA ROCHE LTD. (CH) | 2015-08-19 | — | — | CN | disclosed |
| CN-102516241-B | The azabicyclic alkane derivatives of the bicyclic heterocycle the condensed replacement of CNS activity | Abbott Labaoratories (BS) | 2015-07-29 | — | — | CN | disclosed |
| CN-104203952-A | Imidazopyrrolidinone compounds | NOVARTIS AG | 2014-12-10 | — | — | CN | disclosed |
| CN-102203065-B | Novel phenylamide or pyridylamide derivatives and their use as GPBAR1 agonists | HOFFMANN LA ROCHE | 2014-07-09 | — | — | CN | disclosed |
| CN-102341388-B | Substituted benzazoles, benzimidazoles, azolopyridines and imidazopyridine derivatives as gamma secretase modulators | JANSSEN PHARMACEUTICALS INC | 2014-05-07 | — | — | CN | disclosed |
| CN-102143940-B | Cyclohexyl amide derivatives as CRF-1 receptor antagonists and uses thereof | NOVARTIS AG | 2014-04-16 | — | — | CN | disclosed |
| CN-101679410-B | 2-[(2-substituted)-ind0lizin-3-yl]-2-oxo-acetamide derivatives as antifungal agents | F2G LTD | 2013-11-27 | — | — | CN | disclosed |
| CN-101835772-B | Novel imidazole derivatives | SYNGENTA PARTICIPATIONS AG | 2013-11-06 | — | — | CN | disclosed |
| CN-101808994-B | Compounds and methods for kinase modulation, and indications therefor | PLEXXIKON INC | 2013-05-15 | — | — | CN | disclosed |
| CN-101715450-B | Azaindole derivatives as CFTR modulators | VERTEX PHARMA | 2013-03-13 | — | — | CN | disclosed |
| CN-102341388-A | Novel substituted benzazoles, benzimidazoles, azolopyridines and imidazopyridine derivatives as gamma secretase modulators | ORTHO MCNEIL JANSSEN PHARM | 2012-02-01 | — | — | CN | disclosed |
| CN-102325765-A | Novel substituted bicyclic heterocyclic compounds as gamma secretase modulators | ORTHO MCNEIL JANSSEN PHARM | 2012-01-18 | — | — | CN | disclosed |