SCHEMBL27831799

SCHEMBL27831799

COCC(=O)Nc1ccc(C(=O)CCl)c(OC)c1

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HPGD P15428 5/20 0.53
SMN1; SMN2 Q16637 3/20 0.52
KDM4C Q9H3R0 1/20 0.52
ALDH1A1 P00352 4/20 0.50
KMT2A Q03164 2/20 0.48
KDM4E B2RXH2 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
NPSR1 Q6W5P4 1/20 0.47
MAPT P10636 2/20 0.47
CYP2C19 P33261 1/20 0.47
ALOX12 P18054 1/20 0.47
MAPK1 P28482 1/20 0.47
HTT P42858 1/20 0.47
MTNR1A P48039 1/20 0.46
MTNR1B P49286 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8752457 0.89 KDM4C (0.56) HPGDSMN1; SMN2KDM4CALDH1A1KMT2A
SCHEMBL2492405 0.85 TDP1 (0.55) SMN1; SMN2ALDH1A1KMT2AMAPTMAPK1
SCHEMBL28099565 0.81 SMN1; SMN2 (0.75) HPGDSMN1; SMN2KDM4CALDH1A1KMT2A
SCHEMBL9298899 0.80 HPGD (0.67) HPGDSMN1; SMN2KDM4CALDH1A1KDM4E
SCHEMBL28147929 0.79 LMNA (0.43) SMN1; SMN2ALDH1A1KMT2AKDM4EMAPT
SCHEMBL5208087 0.79 TDP1 (0.55) SMN1; SMN2ALDH1A1KMT2AMAPTMAPK1
SCHEMBL8752446 0.78 ALDH1A1 (0.54) HPGDSMN1; SMN2ALDH1A1KMT2AKDM4E
SCHEMBL10658526 0.77 SMN1; SMN2 (0.57) HPGDSMN1; SMN2KDM4CALDH1A1KMT2A
SCHEMBL28127391 0.77 MAPT (0.50) SMN1; SMN2ALDH1A1KMT2AL3MBTL1MAPT
SCHEMBL20679550 0.75 SMN1; SMN2 (0.66) HPGDSMN1; SMN2ALDH1A1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104194392-B The preparation method of inorganic-organic hybrid yellow ultramarine TIANJIN CHENGJIAN UNIVERSITY (CN) 2015-12-30 CN claimed
CN-104194392-A Preparation method of inorganic and organic composite yellow pigment UNIV TIANJIN CHENGJIAN 2014-12-10 CN claimed
CN-104479394-B AZOpigments continuous preparation method in branch's serpentine pipe 苏州世名科技股份有限公司 2016-06-08 CN disclosed
CN-104194392-B The preparation method of inorganic-organic hybrid yellow ultramarine TIANJIN CHENGJIAN UNIVERSITY (CN) 2015-12-30 CN disclosed
CN-104479394-A Method for continuously preparing azo pigment in branch spiral tube SUZHOU SUNMUN TECHNOLOGY CO LTD 2015-04-01 CN disclosed
CN-104194392-A Preparation method of inorganic and organic composite yellow pigment UNIV TIANJIN CHENGJIAN 2014-12-10 CN disclosed
CN-102304078-A 1, 4-dihydropyridine compound containing acetoacetanilide structure and preparation method thereof NANJING UNIVERSITY OF TECHNOLOGY 2012-01-04 CN disclosed