Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRAP1 | Q12931 | 9/20 | 0.42 |
| ▸ | HSP90B1 | P14625 | 7/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27811666 | 0.87 | ALDH1A1 (0.38) | TRAP1HSP90B1LMNAMAPT | |
| SCHEMBL27811590 | 0.81 | LMNA (0.36) | TRAP1HSP90B1HSP90AA1LMNA | |
| SCHEMBL27641134 | 0.78 | HSP90AA1 (0.48) | TRAP1HSP90B1HSP90AA1 | |
| SCHEMBL27831857 | 0.76 | HSP90AA1 (0.35) | TRAP1HSP90B1HSP90AA1 | |
| SCHEMBL27811517 | 0.75 | TRAP1 (0.34) | TRAP1HSP90B1HSP90AA1 | |
| SCHEMBL28787805 | 0.75 | TRAP1 (0.36) | TRAP1HSP90B1HSP90AA1 | |
| SCHEMBL27831914 | 0.74 | TRAP1 (0.33) | TRAP1HSP90B1HSP90AA1 | |
| SCHEMBL27641254 | 0.74 | HSP90AA1 (0.49) | HSP90AA1 | |
| SCHEMBL1052264 | 0.73 | TRAP1 (0.73) | TRAP1HSP90B1HSP90AA1KDM4EMAPT | |
| SCHEMBL27831901 | 0.72 | TRAP1 (0.43) | TRAP1HSP90B1KDM4ELMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102098918-A | Bioactive compounds for treatment of cancer and neurodegenerative diseases | PONIARD PHARMACEUTICALS INC | 2011-06-15 | — | — | CN | disclosed |