Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VNN1 | O95497 | 11/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 7/20 | 0.34 |
| ▸ | KIF18A | Q8NI77 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2784105 | 0.89 | VNN1 (0.35) | VNN1RIPK1KIF18A | |
| SCHEMBL1326997 | 0.84 | MAPK1 (0.35) | — | |
| SCHEMBL2781830 | 0.77 | MAPK1 (0.31) | RIPK1 | |
| SCHEMBL2783201 | 0.76 | CKS1B (0.33) | — | |
| SCHEMBL2784108 | 0.71 | CKS1B (0.37) | — | |
| SCHEMBL2781837 | 0.65 | — | — | |
| SCHEMBL28935821 | 0.65 | RIPK1 (0.40) | VNN1RIPK1 | |
| SCHEMBL17960320 | 0.64 | GRM5 (0.39) | — | |
| SCHEMBL2110457 | 0.63 | HCAR3 (0.41) | RIPK1 | |
| SCHEMBL20305088 | 0.62 | PIK3CA (0.39) | RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010147226-A1 | PYRAZINOOXAZEPINE DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-12-23 | — | — | WO | disclosed |