Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 8/20 | 0.39 |
| ▸ | THRB | P10828 | 8/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18290201 | 0.88 | THRA (0.51) | THRATHRBTRPV1PKMCYP1A2 | |
| SCHEMBL28299901 | 0.88 | ALDH1A1 (0.35) | THRATHRBPKMCYP1A2MAPT | |
| SCHEMBL18290236 | 0.83 | ALDH1A1 (0.35) | THRATHRBPKMCYP1A2NPSR1 | |
| SCHEMBL18290221 | 0.80 | THRA (0.38) | THRATHRBTRPV1PKMCYP1A2 | |
| SCHEMBL18290244 | 0.75 | TRPV1 (0.33) | THRATHRBTRPV1PKMCYP1A2 | |
| SCHEMBL18290202 | 0.74 | LMNA (0.33) | THRATHRBTRPV1CYP1A2MAPT | |
| SCHEMBL18290231 | 0.69 | CASR (0.32) | THRATHRBTRPV1CYP1A2MAPT | |
| SCHEMBL21013101 | 0.67 | IAPP (0.46) | THRATHRBCYP1A2MAPTCYP3A4 | |
| SCHEMBL2964707 | 0.67 | CYP1A2 (0.48) | THRBTRPV1PKMCYP1A2MAPT | |
| SCHEMBL10022399 | 0.63 | GRIN2D (0.49) | THRBTRPV1PKMCYP1A2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102295545-A | Method for biosynthesizing abietane diterpenoid compounds by using cephalotaxus fortune culture cells | — | 2011-12-28 | — | — | CN | claimed |
| CN-102295545-B | Method for biosynthesizing abietane diterpenoid compounds by using cephalotaxus fortune culture cells | DALIAN CHEMICAL PHYSICS INST | 2013-12-04 | — | — | CN | disclosed |
| CN-102295545-A | Method for biosynthesizing abietane diterpenoid compounds by using cephalotaxus fortune culture cells | — | 2011-12-28 | — | — | CN | disclosed |