Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.67 |
| ▸ | NPC1 | O15118 | 4/20 | 0.67 |
| ▸ | RAB9A | P51151 | 4/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | TP53 | P04637 | 2/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | HPGDS | O60760 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1366372 | 0.78 | L3MBTL1 (0.56) | MAPTNPC1RAB9ALMNATP53 | |
| SCHEMBL2970766 | 0.76 | L3MBTL1 (0.52) | MAPTNPC1RAB9ATP53HPGDS | |
| SCHEMBL2981893 | 0.76 | SLC18A3 (0.50) | MAPTNPC1RAB9ATP53HPGDS | |
| SCHEMBL3763231 | 0.76 | FAAH (0.61) | HPGDSSMN1; SMN2L3MBTL1FAAHSCN9A | |
| Cyanide SCHEMBL27913373 | 0.76 | L3MBTL1 (0.57) | MAPTNPC1RAB9ALMNATP53 | |
| SCHEMBL18711879 | 0.74 | FAAH (0.59) | TP53MAPK1HPGDSSMN1; SMN2HSD17B10 | |
| SCHEMBL2297392 | 0.74 | HPGDS (0.78) | MAPTNPC1RAB9ALMNATP53 | |
| SCHEMBL25393063 | 0.73 | NPC1 (0.46) | MAPTNPC1RAB9ALMNATP53 | |
| SCHEMBL25394959 | 0.73 | NPC1 (0.46) | MAPTNPC1RAB9ALMNATP53 | |
| SCHEMBL25393059 | 0.73 | NPC1 (0.46) | MAPTNPC1RAB9ALMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102099354-B | Azole compound | ASTELLAS PHARMA INC | 2013-07-10 | — | — | CN | disclosed |
| CN-102099354-A | Azole compound | ASTELLAS PHARMA INC | 2011-06-15 | — | — | CN | disclosed |