Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 4/20 | 0.43 |
| ▸ | BCL2 | P10415 | 1/20 | 0.42 |
| ▸ | SMYD2 | Q9NRG4 | 2/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | DRD4 | P21917 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.38 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1954789 | 0.84 | BCL2 (0.58) | BCL2 | |
| SCHEMBL1955329 | 0.74 | BCL2 (0.61) | BCL2 | |
| SCHEMBL27831940 | 0.73 | HRH3 (0.49) | BCL2HTR1ADRD2DRD3HRH1 | |
| SCHEMBL1742850 | 0.72 | BCL2 (0.63) | BCL2 | |
| SCHEMBL1958460 | 0.71 | BCL2 (0.48) | HTR7BCL2DRD2DRD4DRD3 | |
| SCHEMBL1957923 | 0.70 | BCL2 (0.49) | BCL2 | |
| SCHEMBL27831837 | 0.70 | HTR1A (0.49) | HTR1ADRD2DRD3HRH1 | |
| SCHEMBL12991997 | 0.69 | KCNH2 (0.48) | — | |
| SCHEMBL1957460 | 0.69 | BCL2 (0.53) | BCL2 | |
| SCHEMBL1959356 | 0.68 | BCL2 (0.52) | BCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102307622-A | Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases | ABBOTT LAB | 2012-01-04 | — | — | CN | disclosed |