Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ACP3 | P15309 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27835482 | 1.00 | CASP1 (0.45) | CASP1TSHRADRB2ADRB1AOC3 | |
| SCHEMBL14710510 | 0.81 | ALDH1A1 (0.48) | CASP1TSHRADRB2ADRB1ALDH1A1 | |
| SCHEMBL19451976 | 0.81 | ALDH1A1 (0.48) | CASP1TSHRADRB2ADRB1ALDH1A1 | |
| SCHEMBL8934234 | 0.81 | CASP1 (0.42) | CASP1TSHRADRB2ADRB1AOC3 | |
| SCHEMBL26242470 | 0.81 | CASP1 (0.42) | CASP1TSHRADRB2ADRB1AOC3 | |
| SCHEMBL9724510 | 0.80 | CASP1 (0.41) | CASP1TSHRAOC3CYP2D6NFKB1 | |
| SCHEMBL4075794 | 0.80 | CASP1 (0.41) | CASP1TSHRADRB2ADRB1AOC3 | |
| SCHEMBL8867146 | 0.79 | TSHR (0.48) | CASP1TSHRADRB2ADRB1AOC3 | |
| SCHEMBL29845650 | 0.79 | TSHR (0.48) | CASP1TSHRALDH1A1ACP3CYP3A4 | |
| SCHEMBL29973372 | 0.79 | TSHR (0.48) | CASP1TSHRALDH1A1ACP3CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101903317-A | Improved process for the preparation of 2- (substituted phenyl) -2 hydroxy-ethylcarbamates | JANSSEN PHARMACEUTICA NV | 2010-12-01 | — | — | CN | claimed |
| CN-101903317-A | Improved process for the preparation of 2- (substituted phenyl) -2 hydroxy-ethylcarbamates | JANSSEN PHARMACEUTICA NV | 2010-12-01 | — | — | CN | disclosed |