SCHEMBL9724510

SCHEMBL9724510

CC(=O)OC(N)c1ccccc1Cl

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CASP1 P29466 1/20 0.41
TSHR P16473 1/20 0.41
AOC3 Q16853 1/20 0.40
IDO1 P14902 2/20 0.40
TDO2 P48775 2/20 0.40
IDO2 Q6ZQW0 2/20 0.40
CYP3A4 P08684 2/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2D6 P10635 1/20 0.39
NFKB1 P19838 1/20 0.39
PNMT P11086 1/20 0.39
NISCH Q9Y2I1 1/20 0.39
ALDH1A1 P00352 2/20 0.38
LMNA P02545 1/20 0.38
GLA P06280 1/20 0.38
CXCL8 P10145 1/20 0.38
ACP3 P15309 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14710510 0.80 ALDH1A1 (0.48) CASP1TSHRCYP3A4ALDH1A1LMNA
SCHEMBL19451976 0.80 ALDH1A1 (0.48) CASP1TSHRCYP3A4ALDH1A1LMNA
SCHEMBL27835482 0.80 CASP1 (0.45) CASP1TSHRAOC3IDO1TDO2
SCHEMBL27835481 0.80 CASP1 (0.45) CASP1TSHRAOC3IDO1TDO2
SCHEMBL4075794 0.79 CASP1 (0.41) CASP1TSHRAOC3IDO1TDO2
SCHEMBL27737972 0.79 ALDH1A1 (0.38) TSHRCYP3A4ALDH1A1
SCHEMBL8867146 0.77 TSHR (0.48) CASP1TSHRAOC3IDO1TDO2
SCHEMBL19451943 0.77 TSHR (0.48) CASP1TSHRIDO1TDO2IDO2
SCHEMBL29973372 0.77 TSHR (0.48) CASP1TSHRIDO1TDO2IDO2
SCHEMBL8069967 0.77 TSHR (0.48) CASP1TSHRIDO1TDO2IDO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4230387-A None JP disclosed
JP-H04230387-A PRODUCTION OF N-PHENYLACETIC ACID DERIVATIVE OF THETRAHYDROTHIENO(3,2-C)PYRIDINE AND ITS INTERMEDIATE SANOFI SA 1992-08-19 JP disclosed