Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.62 |
| ▸ | TNKS | O95271 | 2/20 | 0.62 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.62 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 2/20 | 0.58 |
| ▸ | CA12 | O43570 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.54 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.54 |
| ▸ | CA9 | Q16790 | 2/20 | 0.54 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27835673 | 0.91 | MAPT (0.64) | TNKSSIGMAR1ABCG2KDM4EMAPT | |
| SCHEMBL12940261 | 0.82 | CYP19A1 (0.68) | CYP19A1TNKSSIGMAR1ABCG2KDM4E | |
| SCHEMBL13592819 | 0.82 | CYP19A1 (0.68) | CYP19A1TNKSSIGMAR1ABCG2KDM4E | |
| SCHEMBL9140701 | 0.82 | KDM4E (0.74) | CYP19A1TNKSSIGMAR1ABCG2KDM4E | |
| SCHEMBL28078087 | 0.81 | MAOB (0.67) | CYP19A1TNKSSIGMAR1ABCG2KDM4E | |
| SCHEMBL7933564 | 0.81 | SIGMAR1 (0.73) | CYP19A1TNKSSIGMAR1ABCG2KDM4E | |
| SCHEMBL9199489 | 0.80 | SIGMAR1 (0.72) | CYP19A1TNKSSIGMAR1ABCG2KDM4E | |
| SCHEMBL10025659 | 0.80 | SIGMAR1 (0.76) | CYP19A1TNKSSIGMAR1ABCG2KDM4E | |
| SCHEMBL9391105 | 0.80 | SIGMAR1 (0.72) | CYP19A1TNKSSIGMAR1ABCG2KDM4E | |
| SCHEMBL7372368 | 0.80 | SIGMAR1 (0.72) | CYP19A1TNKSSIGMAR1ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101143861-B | B ring 4'-single substituted flavone compounds, preparation method and use | SHANGHAI INST MATERIA MEDICA | 2011-08-03 | — | — | CN | disclosed |