Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.63 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.63 |
| ▸ | SIGMAR1 | Q99720 | 13/20 | 0.63 |
| ▸ | STS | P08842 | 1/20 | 0.58 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.57 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.57 |
| ▸ | TNKS | O95271 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27835580 | 0.91 | CYP19A1 (0.62) | MAPTKDM4ENPC1RAB9AABCB1 | |
| SCHEMBL7605927 | 0.82 | MAPT (0.73) | MAPTKDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL28632889 | 0.82 | ABCB1 (0.73) | MAPTKDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL27835584 | 0.82 | SIGMAR1 (0.76) | MAPTKDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL27816181 | 0.82 | MAPT (0.70) | MAPTKDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL28647889 | 0.80 | SIGMAR1 (0.78) | MAPTKDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL28646380 | 0.79 | ABCB1 (0.68) | MAPTKDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL8786926 | 0.79 | SIGMAR1 (0.78) | MAPTKDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL8786565 | 0.78 | SIGMAR1 (0.80) | SIGMAR1 | |
| SCHEMBL8786494 | 0.78 | SIGMAR1 (0.77) | MAPTKDM4ENPC1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101143861-B | B ring 4'-single substituted flavone compounds, preparation method and use | SHANGHAI INST MATERIA MEDICA | 2011-08-03 | — | — | CN | disclosed |