Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.48 |
| ▸ | CTSV | O60911 | 2/20 | 0.47 |
| ▸ | CTSL | P07711 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | PDE9A | O76083 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28740845 | 0.95 | KDM4E (0.44) | OXER1CTSVCTSLKDM4EALDH1A1 | |
| SCHEMBL27350234 | 0.82 | PDE9A (0.50) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL5409935 | 0.78 | CHRNB2 (0.60) | OXER1CTSVCTSLKDM4EALDH1A1 | |
| SCHEMBL6330362 | 0.78 | OXER1 (0.56) | OXER1CTSVCTSLKDM4EALDH1A1 | |
| SCHEMBL9285803 | 0.77 | KDM4E (0.54) | CTSVCTSLKDM4EALDH1A1HPGD | |
| SCHEMBL1252201 | 0.76 | PDE9A (0.45) | KDM4EALDH1A1HPGDHSD17B10PDE9A | |
| SCHEMBL28674730 | 0.76 | CHRNB2 (0.59) | OXER1CTSVCTSLKDM4EALDH1A1 | |
| SCHEMBL31091563 | 0.76 | CHRNB2 (0.59) | OXER1CTSVCTSLKDM4EALDH1A1 | |
| SCHEMBL11393743 | 0.76 | OXER1 (0.51) | OXER1CTSVCTSLKDM4EALDH1A1 | |
| SCHEMBL29355024 | 0.75 | KDM4E (0.65) | OXER1CTSVCTSLKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102020601-B | Method for synthesizing N-aryl indole-3-nitrile derivative | UNIV TIANJIN | 2012-10-24 | — | — | CN | claimed |
| CN-102020601-A | Method for synthesizing N-aryl indole-3-nitrile derivative | UNIV TIANJIN | 2011-04-20 | — | — | CN | claimed |
| CN-102020601-B | Method for synthesizing N-aryl indole-3-nitrile derivative | UNIV TIANJIN | 2012-10-24 | — | — | CN | disclosed |
| CN-102020601-A | Method for synthesizing N-aryl indole-3-nitrile derivative | UNIV TIANJIN | 2011-04-20 | — | — | CN | disclosed |