Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | CTSV | O60911 | 2/20 | 0.48 |
| ▸ | CTSL | P07711 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6531687 | 0.86 | KDM4E (0.56) | KDM4EHSD17B10ALDH1A1HPGDGAA | |
| SCHEMBL16297142 | 0.84 | DRD2 (0.46) | KDM4EHSD17B10ALDH1A1HPGDGAA | |
| SCHEMBL31167422 | 0.84 | DRD2 (0.46) | KDM4EHSD17B10ALDH1A1HPGDGAA | |
| SCHEMBL13267812 | 0.82 | DRD2 (0.51) | KDM4EHSD17B10ALDH1A1GAAPOLB | |
| SCHEMBL6533131 | 0.81 | KDM4E (0.55) | KDM4EHSD17B10ALDH1A1HPGDGAA | |
| SCHEMBL4921978 | 0.80 | KDM4E (0.70) | KDM4EHSD17B10ALDH1A1HPGDGAA | |
| SCHEMBL24243724 | 0.80 | HTR2A (0.57) | DRD2DRD4DRD3TSHREGFR | |
| SCHEMBL5409935 | 0.79 | CHRNB2 (0.60) | KDM4EHSD17B10ALDH1A1HPGDGAA | |
| SCHEMBL8444672 | 0.79 | KDM4E (0.68) | KDM4EHSD17B10ALDH1A1HPGDGAA | |
| SCHEMBL8445695 | 0.79 | KDM4E (0.68) | KDM4EHSD17B10ALDH1A1HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5393761-A | Treatment of nervous system disorders | H. LUNDBECK A/S (DK) | 1995-02-28 | — | — | US | disclosed |
| EP-0470039-B1 | Novel 3-arylindole and 3-arylindazole derivatives | LUNDBECK & CO AS H (DK) | 1994-12-07 | — | — | EP | disclosed |
| EP-0470039-A2 | Novel 3-arylindole and 3-arylindazole derivatives | H. LUNDBECK A/S (DK) | 1992-02-05 | — | — | EP | disclosed |