SCHEMBL27836626

SCHEMBL27836626

COc1cc(C2CCCCC2)cc(C2CCCCC2)c1OC

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.46
KDM4E B2RXH2 3/20 0.46
PTAFR P25105 2/20 0.46
POLB P06746 1/20 0.43
HTR2A P28223 2/20 0.42
PDGFRB P09619 1/20 0.42
PDGFRA P16234 1/20 0.42
MAPT P10636 4/20 0.41
TSHR P16473 2/20 0.41
NPSR1 Q6W5P4 2/20 0.41
HPGD P15428 2/20 0.41
HTT P42858 1/20 0.41
CREBBP Q92793 1/20 0.41
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
PTPN1 P18031 1/20 0.40
ACHE P22303 1/20 0.40
TDP1 Q9NUW8 1/20 0.38
PDE4A P27815 1/20 0.38
PDE4B Q07343 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11529728 0.81 ALDH1A1 (0.44) ALDH1A1KDM4EPTAFRPOLBHTR2A
SCHEMBL29267402 0.79 PTAFR (0.62) ALDH1A1KDM4EPTAFRMAPTTSHR
SCHEMBL2957351 0.75 HTR2A (0.64) HTR2A
SCHEMBL2094053 0.75 PDE4A (0.54) ALDH1A1KDM4EHTR2APDGFRBPDGFRA
SCHEMBL11763395 0.74 PTAFR (0.56) ALDH1A1KDM4EPTAFRMAPTTSHR
SCHEMBL6966081 0.74 PDGFRB (0.39) ALDH1A1KDM4EPTAFRHTR2APDGFRB
SCHEMBL14793041 0.74 KMO (0.33) KDM4EMAPTMEN1KMT2ATDP1
SCHEMBL14827794 0.74 HTR2C (0.49) ALDH1A1KDM4EMAPTTSHRMEN1
SCHEMBL12299723 0.73 ALDH1A1 (0.39) ALDH1A1KDM4EPOLBHTR2AMAPT
SCHEMBL12704114 0.73 ACHE (0.59) ALDH1A1KDM4EPTAFRPOLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102005619-A Redox couple for lithium ion battery overcharge-resistant mixed additive HEFEI LI XIN ENERGY MATERIALS CO LTD 2011-04-06 CN disclosed