Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 2/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | ANPEP | P15144 | 4/20 | 0.42 |
| ▸ | LAP3 | P28838 | 4/20 | 0.42 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.35 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | METAP1 | P53582 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27766170 | 0.80 | TSHR (0.33) | MMP1MMP8ANPEPLAP3ERAP1 | |
| Phosphoric Acid SCHEMBL159670 | 0.76 | LAP3 (0.48) | MMP1MMP8ANPEPLAP3ERAP1 | |
| Isobutanol SCHEMBL11423920 | 0.76 | TSHR (0.64) | MMP1MMP8ANPEPLAP3ERAP1 | |
| Phosphoric Acid SCHEMBL4629639 | 0.76 | LAP3 (0.48) | MMP1MMP8ANPEPLAP3ERAP1 | |
| Phosphoric Acid SCHEMBL29043726 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL395148 | 0.73 | — | — | |
| Iodide SCHEMBL393808 | 0.73 | — | — | |
| Phosphoric Acid SCHEMBL5901916 | 0.73 | CA2 (0.50) | MMP1MMP8ANPEPLAP3ERAP1 | |
| Phosphoric Acid SCHEMBL15540730 | 0.73 | CA2 (0.50) | MMP1MMP8ANPEPLAP3ERAP1 | |
| Phosphoric Acid SCHEMBL571124 | 0.73 | CA2 (0.50) | MMP1MMP8ANPEPLAP3ERAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105647614-A | Anti-wear assembly for lubricating transmission system device and method | 路博润公司 | 2016-06-08 | — | — | CN | disclosed |
| CN-102037108-A | Antiwear composition and method for lubricating driveline components | LUBRIZOL CORP | 2011-04-27 | — | — | CN | disclosed |