Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.37 |
| ▸ | ILK | Q13418 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
| ▸ | RXRG | P48443 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27854827 | 0.88 | CNR1 (0.43) | CNR1CNR2ALOX5PDPK1TLR7 | |
| SCHEMBL27854817 | 0.86 | CTSK (0.47) | CNR1CNR2ALOX5TLR8PTGS2 | |
| SCHEMBL27682759 | 0.85 | NPC1 (0.49) | CNR1CNR2ALOX5NPY5RTLR7 | |
| Ammonia Solution, Strong SCHEMBL27702328 | 0.83 | NPC1 (0.48) | CNR1CNR2ALOX5NPY5RTLR7 | |
| SCHEMBL2364213 | 0.83 | NPC1 (0.53) | CNR1CNR2ALOX5NPY5RTLR7 | |
| SCHEMBL27702044 | 0.83 | CNR2 (0.46) | CNR1CNR2ALOX5TLR7 | |
| SCHEMBL19731925 | 0.82 | MIF (0.46) | CNR1CNR2ALOX5PTGS2TLR7 | |
| SCHEMBL27742972 | 0.82 | NPC1 (0.51) | CNR1CNR2ALOX5PDPK1TLR7 | |
| SCHEMBL27702016 | 0.82 | CNR2 (0.48) | CNR1CNR2ALOX5KCNH2TLR7 | |
| SCHEMBL27742966 | 0.81 | CNR1 (0.61) | CNR1CNR2ALOX5TLR7RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102026985-A | Quinazoline derivatives as RAF kinase modulators and methods and uses thereof | AMBIT BIOSCIENCES CORPORATON | 2011-04-20 | — | — | CN | disclosed |