SCHEMBL27840323

SCHEMBL27840323

CC(C)c1ccc(-c2cs[c]n2)cc1CN

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PRMT5 O14744 1/20 0.31
WDR77 Q9BQA1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27840328 0.89
SCHEMBL2398609 0.80 KDM4E (0.31)
SCHEMBL971162 0.71 RAB9A (0.39)
SCHEMBL468037 0.67 CTSK (0.41)
SCHEMBL1916781 0.67 XDH (0.41)
SCHEMBL2398190 0.67 CTSK (0.39)
SCHEMBL17626276 0.66 CDC25A (0.51)
SCHEMBL17626046 0.65 KMT2A (0.48)
SCHEMBL3849204 0.65 SLC6A2 (0.50)
SCHEMBL26137536 0.65 HTR1D (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102245574-A Compounds, pharmaceutical compositions and methods for treating metabolic disorders EUROSCREEN SA 2011-11-16 CN claimed
CN-102245574-A Compounds, pharmaceutical compositions and methods for treating metabolic disorders EUROSCREEN SA 2011-11-16 CN disclosed