Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.43 |
| ▸ | POLB | P06746 | 6/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.40 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | PKM | P14618 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAT2A | P31153 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28945494 | 0.90 | TP53 (0.43) | KEAP1L3MBTL1POLBTDP1CTDSP1 | |
| SCHEMBL28795749 | 0.84 | KMT2A (0.40) | KEAP1L3MBTL1POLBTDP1CTDSP1 | |
| SCHEMBL28774879 | 0.78 | METAP2 (0.39) | KEAP1L3MBTL1POLBTDP1CTDSP1 | |
| SCHEMBL28355967 | 0.74 | ESR2 (0.43) | PTGS1MEN1KMT2ATSHRHTT | |
| Hydrochloric Acid SCHEMBL28562155 | 0.72 | ESR2 (0.42) | PTGS1MEN1KMT2ATSHRPTPN1 | |
| SCHEMBL27732259 | 0.72 | PTGER2 (0.40) | POLBTDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL5052040 | 0.71 | L3MBTL1 (0.47) | KEAP1L3MBTL1POLBTDP1CTDSP1 | |
| SCHEMBL11139556 | 0.71 | ESR2 (0.43) | PTGS1MEN1KMT2ATSHRHTT | |
| SCHEMBL17459516 | 0.71 | PTPN1 (0.51) | PTGS1ALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL9153943 | 0.71 | ESR2 (0.43) | PTGS1MEN1KMT2ATSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101547919-B | Dihydropyrimidine compounds and application thereof in preparing medicaments for treating and preventing viral diseases | BEIJING MOLIK SCIENCE AND TECHNOLOGY CO LTD | 2011-11-16 | — | — | CN | claimed |
| CN-101547919-B | Dihydropyrimidine compounds and application thereof in preparing medicaments for treating and preventing viral diseases | BEIJING MOLIK SCIENCE AND TECHNOLOGY CO LTD | 2011-11-16 | — | — | CN | disclosed |