Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.47 |
| ▸ | POLB | P06746 | 6/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.44 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5546498 | 0.82 | L3MBTL1 (0.43) | L3MBTL1POLBTDP1CTDSP1KDM4E | |
| SCHEMBL18920540 | 0.81 | MYC (0.53) | L3MBTL1POLBTDP1CTDSP1KDM4E | |
| SCHEMBL27596775 | 0.75 | PTPN1 (0.47) | L3MBTL1POLBTDP1CTDSP1KDM4E | |
| SCHEMBL2875497 | 0.75 | FABP4 (0.51) | KDM4EKMT2AALDH1A1HSD17B10HPGD | |
| SCHEMBL18920575 | 0.71 | KEAP1 (0.44) | L3MBTL1POLBTDP1CTDSP1KDM4E | |
| SCHEMBL28869121 | 0.71 | PTPN1 (0.52) | L3MBTL1POLBTDP1CTDSP1KDM4E | |
| SCHEMBL26259596 | 0.70 | TAAR1 (0.42) | L3MBTL1POLBTDP1CTDSP1KDM4E | |
| Benzene SCHEMBL28845411 | 0.70 | ALDH1A1 (0.46) | POLBTDP1KDM4EMEN1KMT2A | |
| SCHEMBL1127114 | 0.70 | L3MBTL1 (0.44) | L3MBTL1POLBTDP1CTDSP1KDM4E | |
| SCHEMBL25529106 | 0.70 | L3MBTL1 (0.44) | L3MBTL1POLBTDP1CTDSP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080075413-A1 | THERMALLY REVERSIBLY CROSSLINKABLE POLYMER AS CLADDING MATERIAL FOR ELECTRO-OPTIC DEVICES | AIR FORCE, UNITED STATES | 2008-03-27 | — | — | US | disclosed |
| US-7346259-B1 | Thermally reversibly crosslinkable polymer as cladding material for electro-optic devices | UNIVERSITY OF WASHINGTON (US) | 2008-03-18 | — | — | US | disclosed |