Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28806027 | 0.80 | ITGB2 (0.46) | HIF1AHRH3HRH4CYP19A1TAAR1 | |
| SCHEMBL226163 | 0.76 | CYP19A1 (0.58) | HRH3HRH4KCNH2CYP19A1TAAR1 | |
| SCHEMBL27867611 | 0.75 | KMT2A (0.39) | CYP3A4 | |
| SCHEMBL8710389 | 0.73 | EPHX1 (0.44) | TAAR1 | |
| SCHEMBL27679351 | 0.72 | GLS (0.32) | CYP3A4 | |
| SCHEMBL27679469 | 0.72 | LMNA (0.36) | — | |
| SCHEMBL222295 | 0.72 | HRH3 (0.56) | HRH3HRH4KCNH2CYP19A1TAAR1 | |
| SCHEMBL28827075 | 0.71 | GLS (0.32) | — | |
| SCHEMBL28027221 | 0.70 | ADRA2A (0.56) | — | |
| SCHEMBL28290101 | 0.70 | PARP1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102186825-A | Aryl gpr120 receptor agonists and uses thereof | METABOLEX INC | 2011-09-14 | — | — | CN | disclosed |