Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15610865 | 0.81 | KMT2A (0.55) | SMN1; SMN2OPRM1OPRD1KMT2AL3MBTL1 | |
| SCHEMBL27842003 | 0.81 | EPHX2 (0.40) | SMN1; SMN2L3MBTL1MAPTHTTHPGD | |
| SCHEMBL27822931 | 0.81 | LMNA (0.50) | SMN1; SMN2KMT2AL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL27822933 | 0.81 | ALDH1A1 (0.43) | SMN1; SMN2KMT2AL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL1625677 | 0.79 | MAOB (0.47) | ALDH1A1MAPTPOLB | |
| SCHEMBL1578801 | 0.79 | ALDH1A1 (0.49) | SMN1; SMN2OPRM1OPRD1KMT2AL3MBTL1 | |
| SCHEMBL15610864 | 0.78 | KMT2A (0.54) | SMN1; SMN2OPRM1OPRD1KMT2AL3MBTL1 | |
| SCHEMBL16375025 | 0.76 | KMT2A (0.52) | SMN1; SMN2OPRM1OPRD1KMT2AL3MBTL1 | |
| SCHEMBL10996751 | 0.75 | MAPT (0.53) | SMN1; SMN2KMT2AALDH1A1MEN1MAPT | |
| SCHEMBL5067751 | 0.73 | ALDH1A1 (0.57) | KMT2AL3MBTL1ALDH1A1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102159535-A | Potassium ion channel modulators and uses thereof | UNIV RAMOT | 2011-08-17 | — | — | CN | disclosed |