Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 8/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.39 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2510160 | 0.82 | LMNA (0.52) | LMNAALDH1A1MEN1KMT2ARECQL | |
| SCHEMBL27841981 | 0.81 | ALDH1A1 (0.37) | LMNAALDH1A1SMN1; SMN2GAA | |
| SCHEMBL27841972 | 0.81 | SMN1; SMN2 (0.48) | ALDH1A1MEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL27822933 | 0.80 | ALDH1A1 (0.43) | LMNAALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2339087 | 0.75 | LMNA (0.55) | LMNAALDH1A1MEN1KMT2ARECQL | |
| SCHEMBL5735718 | 0.74 | ALDH1A1 (0.55) | LMNAALDH1A1MEN1KMT2ARECQL | |
| SCHEMBL29875166 | 0.74 | ALDH1A1 (0.55) | LMNAALDH1A1MEN1KMT2ARECQL | |
| SCHEMBL27842003 | 0.73 | EPHX2 (0.40) | LMNASMN1; SMN2MAPTHTTNPC1 | |
| SCHEMBL19858086 | 0.72 | LMNA (0.47) | LMNAALDH1A1MEN1KMT2ARECQL | |
| SCHEMBL19858089 | 0.72 | LMNA (0.47) | LMNAALDH1A1MEN1KMT2ARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102159535-A | Potassium ion channel modulators and uses thereof | UNIV RAMOT | 2011-08-17 | — | — | CN | disclosed |