Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.44 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.43 |
| ▸ | CPN1 | P15169 | 1/20 | 0.42 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1613696 | 0.98 | HRH1 (0.56) | HRH1CYP2C19EPHX1HTR2ACYP2D6 | |
| Hydrochloric Acid SCHEMBL1093394 | 0.96 | HRH1 (0.54) | HRH1CYP2C19EPHX1HTR2ACYP2D6 | |
| SCHEMBL3781893 | 0.86 | HRH1 (0.59) | HRH1CYP2C19EPHX1HTR2ACYP2D6 | |
| SCHEMBL11115550 | 0.86 | HRH1 (0.56) | HRH1CYP2C19EPHX1HTR2ACYP2D6 | |
| SCHEMBL30371912 | 0.85 | CYP2C19 (0.61) | CYP2C19EPHX1CYP2D6SRCPOLB | |
| SCHEMBL5322781 | 0.85 | HRH1 (0.52) | HRH1CYP2C19EPHX1HTR2ATBXAS1 | |
| SCHEMBL27691659 | 0.84 | EPHX1 (0.61) | HRH1CYP2C19EPHX1HTR2ACYP2D6 | |
| SCHEMBL11502865 | 0.84 | HRH1 (0.54) | HRH1CYP2C19EPHX1HTR2ACYP2D6 | |
| SCHEMBL20850639 | 0.83 | TBXAS1 (0.54) | HRH1CYP2C19EPHX1HTR2ATBXAS1 | |
| SCHEMBL12824732 | 0.82 | HRH1 (0.52) | HRH1CYP2C19EPHX1HTR2AGABBR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102276487-B | Preparation method of trimebutine | YUEYANG YETOP FINE CHEMICAL CO LTD | 2013-06-12 | — | — | CN | disclosed |
| CN-102276487-A | Preparation method of trimebutine | YUEYANG YETOP FINE CHEMICAL CO LTD | 2011-12-14 | — | — | CN | disclosed |