Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 2/20 | 0.56 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.46 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | GLS | O94925 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1613696 | 0.88 | HRH1 (0.56) | HRH1EPHX1HTR2AGABBR2GABBR1 | |
| Hydrochloric Acid SCHEMBL1093394 | 0.86 | HRH1 (0.54) | HRH1EPHX1HTR2AGABBR2GABBR1 | |
| SCHEMBL27843751 | 0.86 | HRH1 (0.54) | HRH1EPHX1HTR2AGABBR2GABBR1 | |
| SCHEMBL11502865 | 0.86 | HRH1 (0.54) | HRH1EPHX1HTR2AGABBR2GABBR1 | |
| SCHEMBL27691659 | 0.86 | EPHX1 (0.61) | HRH1EPHX1HTR2AGABBR2GABBR1 | |
| SCHEMBL12824732 | 0.84 | HRH1 (0.52) | HRH1EPHX1HTR2AGABBR2GABBR1 | |
| SCHEMBL27582649 | 0.83 | GABBR2 (0.53) | EPHX1HTR2AGABBR2GABBR1CYP2C19 | |
| SCHEMBL11122482 | 0.82 | HRH1 (0.50) | HRH1EPHX1HTR2AGABBR2GABBR1 | |
| SCHEMBL28470487 | 0.82 | MMP8 (0.50) | HRH1CYP2D6CYP1A2PKMSMN1; SMN2 | |
| SCHEMBL15653352 | 0.82 | ESR1 (0.46) | CYP2C19LMNAHSD17B10TAAR1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0110748-A1 | Derivatives of phenyl-(3-aminopropyl) ketone, their therapeutical use and process for their preparation | LABORATOIRE L. LAFON Société anonyme dite: (FR) | 1984-06-13 | — | — | EP | disclosed |